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  • Title: The influence of a new antiarrhythmic drug, Craviten (M-71) on the circulatory system in cats.
    Author: Banaszkiewicz W, Chodera A.
    Journal: Pol J Pharmacol Pharm; 1980; 32(6):841-8. PubMed ID: 7243681.
    Abstract:
    Craviten, a newly synthesized ester of optically active 2-aminobutanol-1, produced in cats hypotension and inhibited excitability of sinus node and atrio-ventricular and intraventricular conduction. It acts as a spasmolytic on the isolated rabbit ileum, being approx. 100 times as potent as papaverine. Studies with drugs affecting the vegetative system indicate that the hypotensive and spasmolytic action of Craviten consists in a direct depressing action on smooth musculature.
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