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  • Title: Pharmacokinetic investigations of Craviten. IV. First-pass metabolism in rats.
    Author: Danek A, Witek J.
    Journal: Pol J Pharmacol Pharm; 1980; 32(6):949-53. PubMed ID: 7243692.
    Abstract:
    Pharmacokinetic analysis of serum levels of Craviten found after oral and iv injection suggests, that the examined drug has a relatively low systemic availability. This lack of availability may be attributed to the metabolism of Craviten during the first passage into the circulation after oral administration.
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