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  • Title: [Intracellular ribonucleases from Penicillin brevicompactum and their natural inhibitors].
    Author: Zigel' M, Bezborodov AM.
    Journal: Prikl Biokhim Mikrobiol; 1981; 17(2):203-9. PubMed ID: 7243745.
    Abstract:
    The ability of the fungus Penicillium brevi-compactum for the synthesis of intracellular ribonucleases and their inhibitors was examined. Activities of ribonucleases and their inhibitors were found to vary with the culture growth. As a result of isopropanol precipitation of the cell-free homogenate, ion-exchange chromatography on DEAE-cellulose and gel filtration on Sephadex G-75, two fractions were obtained, they being inhibitor complexes with acid and alkaline intracellular ribonucleases.
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