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  • Title: The relationship between serum bilirubin and reserve albumin for binding of bilirubin during phototherapy of preterm infants.
    Author: Ebbesen F.
    Journal: Acta Paediatr Scand; 1981; 70(3):405-7. PubMed ID: 7246133.
    Abstract:
    Thirty-four preterm newborn infants suffering from uncomplicated hyperbilirubinaemia were studied. The infants received ordinary phototherapy continuously during 48 hours. The serum unconjugated bilirubin concentration decreased significantly during the treatment, and a significant correlation between the changes in the serum bilirubin concentration and the changes in the serum reserve albumin concentration for binding of bilirubin measured by the [14C]MADDS method was found. The regression coefficients were -0.50 and -0.48 after 24 and 48 hours of treatment, respectively. Thus, it can be concluded that the risk of bilirubin encephalopathy is reduced by phototherapy in preterm infants.
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