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  • Title: Metachronous carcinoma complicating Crohn's disease.
    Author: Castellano TJ, Frank MS, Brandt LJ, Mahadevia P.
    Journal: Arch Intern Med; 1981 Jul; 141(8):1074-5. PubMed ID: 7247592.
    Abstract:
    A 63-year-old woman with Crohn's ileocolitis, complicated by ileal adenocarcinoma two years previously, was admitted for examination of weight loss and fatigue. Colonoscopy demonstrated an area of flat, ulcerated mucosa in the sigmoid colon that proved to be an adenocarcinoma in the area of Crohn's colitis; a sigmoid resection and primary anastomosis were performed. Metachronous carcinoma of the large and small bowel occurred in areas involved with Crohn's disease.
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