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  • Title: Physico-chemical properties of new acyl derivatives of tylosin produced by microbial transformation.
    Author: Okamoto R, Fukumoto T, Nomura H, Kiyoshima K, Nakamura K, Takamatsu A, Naganawa H, Takeuchi T, Umezawa H.
    Journal: J Antibiot (Tokyo); 1980 Nov; 33(11):1300-8. PubMed ID: 7251471.
    Abstract:
    By microbial transformation of tylosin (I), the following eight new acyl derivatives were obtained: 3-acetyltylosin (II), 3-propionyltylosin (III), 4"-butyryltylosin (IV), 4"-isovaleryltylosin (V), 3-acetyl-4"-butyryltylosin (VI), 3-acetyl-4"-isovaleryltylosin (VII), 3-propionyl-4"-butyryltylosin (VIII) and 3-propionyl-4"-isovaleryltylosin (IX).
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