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  • Title: Effects of resination on actions of anorexigenic agents.
    Author: Zabik JE, Webb RW, Maickel RP.
    Journal: Methods Find Exp Clin Pharmacol; 1981; 3(3):161-72. PubMed ID: 7253772.
    Abstract:
    The salt and resinated forms of three anorexigenic agents, d-amphetamine, d,1-amphetamine, and phentermine were examined in rats using two test systems. Appetite depression was determined using a deprivation-induced food consumption test and central stimulatory activity was measured by a two-lever continuous avoidance responding task. Dose-response and time-response studies indicated that the resinated forms of all three compounds had a delayed onset of action as anorexigenic agents and a reduced degree of central stimulatory activity as compared to the salt forms.
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