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Pubmed for Handhelds

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  • Title: [Spironolactone in digitalis-requiring cardiac insufficiency following pacemaker implantation].
    Author: Sabin G, Klüsener W.
    Journal: Med Klin; 1981 Jan 02; 76(1):20-3. PubMed ID: 7254119.
    Abstract:
    In a retrospective study conducted in 213 patients with cardiac pacemakers having severe bradycardiac heart failure with oedema, the addition of the aldosterone-antagonist spironolactone to a diuretic therapy was shown to have a favourable influence on the degree of compensation. This has been confirmed in 26 patients under the conditions of a drug interruption period, and in 24 other patients, who were treated with spironolactone after being decompensated under the therapy with digitalis and diuretic or without diuretic. The application of triamterene with a thiazide did not show this positive effect.
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