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  • Title: [Effect of cryoprotectors on stability of lysosomes under cooling].
    Author: Kravchenko LP, Lugovoĭ VI.
    Journal: Ukr Biokhim Zh (1978); 1980; 52(5):573-6. PubMed ID: 7256923.
    Abstract:
    The efficiency of cryoprotectors-polyethylene oxide 400, glycerol, oxyethylated glycerol, dimethyl sulphoxide was studied relative to stabilization isolated lysosomes under different regimes of freezing-thawing. It is established that a decrease in the amount of lysosome hydrolases (RNase, DNase, catepsin D, phosphatase) released to the environment is the most significant in the presence of the mentioned substances uncer slow freezing-thawing.
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