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  • Title: The value of zinc protoporphyrin in equine lead poisoning: a case report.
    Author: Kowalczyk DF, Naylor JM, Gunson D.
    Journal: Vet Hum Toxicol; 1981 Feb; 23(1):12-5. PubMed ID: 7257163.
    Abstract:
    A diagnosis of lead poisoning in a foal was established based on clinical signs and the presence of an elevation in the concentration of blood lead (40 microgram/dl). Additionally, ZPP was determined in whole blood and found to be significantly elevated compared to 10 normal horses not exposed to lead (634 vs 73 microgram/dl). An elevation in ZPP in man has been found to be a sensitive biochemical indicator of lead toxicity even before overt clinical signs are present. This report suggests that ZPP may be a useful screening test for evaluating biological toxicity due to lead in horses and possibly other species.
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