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  • Title: Freeze-fracture studies of muscle caveolae in human muscular dystrophy.
    Author: Bonilla E, Fischbeck K, Schotland DL.
    Journal: Am J Pathol; 1981 Aug; 104(2):167-73. PubMed ID: 7258302.
    Abstract:
    Freeze-fracture studies of caveolar density and distribution were carried out in skeletal muscle plasma membrane from 6 patients with Duchenne muscular dystrophy (DMD), 5 patients with facioscapulohumeral dystrophy (FSH), 5 patients with myotonic dystrophy (MyD) and 5 normal control subjects. The results showed a significant increase in the number of caveolae and a decrease in size in a population of muscle plasma membranes from patients with DMD. No significant changes in the caveolae were observed in muscle plasma membranes from patients with FSH and MyD.
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