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  • Title: Distribution of AChE in cholinergic and non-cholinergic neurons.
    Author: Wallace BG.
    Journal: Brain Res; 1981 Aug 24; 219(1):190-5. PubMed ID: 7260627.
    Abstract:
    Intracellular and surface acetylcholinesterase activities were determined for individual cholinergic and non-cholinergic neurons dissected from the central nervous system of the leech. Echothiophate pretreatment was used to inhibit selectively extracellular enzyme. Cells releasing acetylcholine as a transmitters had approximately 10-fold higher levels of intracellular acetylcholinesterase activity, while all neurons had similar levels of activity associated with the cell surface. These results suggest that intracellular cholinesterase may be a useful marker for cholinergic neurons.
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