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  • Title: Properties and clinical significance of an alkaline phosphatase-lipoprotein-X complex.
    Author: Weijers RN.
    Journal: Clin Chem; 1980 Apr; 26(5):609-12. PubMed ID: 7261306.
    Abstract:
    The existence of an alkaline phosphatase-lipoprotein-X complex was demonstrated as an abnormally moving band in the agar-agarose gel alkaline phosphatase pattern of sera from 58 patients in a group of 72 patients whose sera contained lipoprotein-X. The position of the abnormally moving band in the agar-agarose gel alkaline phosphatase pattern and the percentage of alkaline phosphatase activity in the complex in relation to the total serum alkaline phosphatase activity depend on the serum lipoprotein-X concentration. The presence of the complex is a reliable indicator for cholestasis and of limited value in the differentiation between intrahepatic and extrahepatic cholestasis.
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