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  • Title: 201Thallium stress myocardial imaging: an evaluation of fifty-eight asymptomatic males.
    Author: Nolewajka AJ, Kostuk WJ, Howard J, Rechnitzer PA, Cunningham DA.
    Journal: Clin Cardiol; 1981 May; 4(3):134-8. PubMed ID: 7261488.
    Abstract:
    The possible value of myocardial imaging with 201thallium as a screening procedure for the detection of latent disease has not been previously shown. Fifty-eight asymptomatic men underwent exercise 201thallium imaging together with a risk score profile based on the Framingham criteria for predicting future coronary events. Six subjects (10%) developed perfusion defects compatible with myocardial ischemia. The risk score for the population with an abnormal test was 7.7 +/- 2.9%, compared to 2.0 +/- 2.2% (p less than 0.001) for those men with normal tests. Three of the subjects with abnormal scans underwent selective coronary arteriograms; all three had normal coronary arteries. During a 30-month follow-up, all individuals remained physically active and free of cardiac symptoms. Exercise myocardial imaging is not a cost-effective means of detecting coronary artery disease in an asymptomatic population and should not be used as a screening procedure.
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