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Title: Pituitary-adrenal function after isolated removal of the median eminence in the rat. Author: Merchenthaler I, Lengvári I, Rostás B, Sétáló G. Journal: Endokrinologie; 1981 Apr; 77(2):185-91. PubMed ID: 7262043. Abstract: Removal of the median eminence (ME) resulted in a 30-35 per cent reduction of the weight of the adrenals of female rats as compared to sham-operated controls. Hypophysectomy reduced the adrenal weight by 65-70 per cent during the same period of the time. The question arose as to whether the higher adrenal weight of the ME-ectomized animals reflected partially maintained hypothalamo-hypophyseal-adrenal function. a combined (either + blood withdrawal) stress did not cause significant increase in plasma corticosterone level in animals whose ME was removed 3 weeks earlier. However, 9 weeks following the removal of the ME, female rats responded to the stress. Possible regeneration of axons belonging to the parvicellular neurosecretory system is discussed.[Abstract] [Full Text] [Related] [New Search]