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  • Title: Mitotic and meiotic analysis of a reciprocal translocation t(Y;3) in an azoospermic male.
    Author: Gonzales J, Lesourd S, Dutrillaux B.
    Journal: Hum Genet; 1981; 57(1):111-4. PubMed ID: 7262866.
    Abstract:
    A balanced reciprocal translocation t(Y;3)(q11.2q12) is detected in an azoospermic male, with a normal phenotype. Replication study shows no modification of the replication pattern of the bands of the rearranged chromosomes. Meiotic studies show a chain element at diakinesis. At the pachytene stage, the Y-body is in external contact with the sex vesicle. It is concluded that the integrity of the Y-chromosome is probably necessary for a normal meiotic process, and is more important than dosage effect due to complete or partial disomy of this chromosome.
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