These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A human parathyroid carcinoma that produces parathyroid hormone: long term maintenance in tissue culture.
    Author: Pattillo RA, Ruckert AC, Wilson SD, Hussa RO, Gray RW, Lemann J.
    Journal: J Clin Endocrinol Metab; 1981 Sep; 53(3):641-4. PubMed ID: 7263844.
    Abstract:
    Parathyroid carcinoma cells from a pulmonary metastasis of a patient with a serum Ca of 17 mg/dl and an immunoreactive parathyroid hormone (PTH) of 6.4 ng eq bovine (b) PTH/ml (normal 40--400 pg/ml) have been maintained in tissue culture for more than 2 1/2 years. The cells secrete PTH into the culture media that 1) during immunoassay dilutes in parallel to human hyperparathyroid serum, 2) has a molecular weight similar to intact highly purified bPTH, and 3) stimulates bone resorption in a manner that is equivalent and additive to synthetic bPTH-(1--34).
    [Abstract] [Full Text] [Related] [New Search]