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  • Title: [Effects of tilidin and naloxone on pulmonary function (author's transl)].
    Author: Schaer H, Baasch K.
    Journal: Anaesthesist; 1978 Nov; 27(11):538-9. PubMed ID: 727427.
    Abstract:
    The respiratory depressant effect of tilidine (valoron) was investigated in anaesthetized patients. One hundred mg of tilidine had a slight respiratory depressant effect which was without importance in awake subjects. The respiratory depression caused by tilidine could be antagonized by naloxone while the analgesic effect was maintained. This suggests a dissociation of the mechanisms responsible for the respiratory and the analgesic actions.
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