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  • Title: [Heterocyclic systems. III. Synthesis and CNS activity of derivatives of pyrrole(2,1-c) (1,4)benzodiazocine].
    Author: Massa S, Corelli F, De Martino G, Pantaleoni GC, Fanini D, Palumbo G.
    Journal: Farmaco Sci; 1981 Jun; 36(6):425-31. PubMed ID: 7274434.
    Abstract:
    5,11-Dioxo-1,2,3,5,6,11,12,12a-octahydropyrrolo [2,1-c] [1,4]benzodiazepine and the corresponding 2-hydroxyderivative were prepared by the intramolecular cyclization of 1-(2-aminophenylacetyl)pyrrolidin-2-carboxylic acid and 1-(2-aminophenylacetyl)-4-hydroxypyrrolidin-2-carboxylic acid; some of the tricyclic compounds were tested for neuropsychopharmacological effects.
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