These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A hospital-based survey of radiological sacroiliitis and HLA-B27 and Cw2 in Navajo and Hopi Indians.
    Author: Kuberski TT, Morse HG, Rate RG, Bonnell MD, Wood JG, Bennett PH.
    Journal: Hum Immunol; 1981 Aug; 3(1):77-83. PubMed ID: 7275698.
    Abstract:
    The frequency of radiological sacroiliitis and its association with HLA-B27, Cw1, and Cw2 were determined in Navajo and Hopi Indians coming to a community hospital. In the Navajo, the phenotype frequency of HLA-B27 was 36% and the frequency of sacroiliitis, 11%. In contrast, among the Hopi, the phenotype frequency of HLA-B27 was 9% and the frequency of sacroiliitis, 4%. Of the Navajo men, who had sacroiliitis and were HLA typed, 83% were HLA-B27 positive. The increased frequency of radiological sacroiliitis and were HLA typed, 83% were HLA-B27 positive. The increased frequency of radiological sacroiliitis in the Navajo was felt to be related to the high frequency of HLA-B27 and Reiter's syndrome in this population. HLA-B27, HLA-Cw1, and HLA-Cw2 are known to be in linkage disequilibrium, and about one-half of the men with sacroiliitis from both tribes had concurrence of HLA-B27 and HLA-Cw2.
    [Abstract] [Full Text] [Related] [New Search]