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  • Title: Serum levels of conglutinin, complement, and immunoconglutinin in cattle infected with Anaplasma marginale.
    Author: Rose JE, Amerault TE, Roby TO, Martin WH.
    Journal: Am J Vet Res; 1978 May; 39(5):791-3. PubMed ID: 727576.
    Abstract:
    Sera from 10 splenectomized yearling cattle given massive doses of Anaplasma marginale (peracute cases) were assayed for conglutinin and complement. Sera from 5 nonsplenectomized yearling cattle given smaller doses (acute cases) were assayed for conglutinin, immunoconglutinin, and complement. In the peracute cases, conglutinating activity disappeared within 6 days after the cattle inoculated. In the acute cases, conglutining began to disappear at 3 weeks after inoculation and had disappeared at peak parasitemia at 4 weeks. Conglutinin returned by 7 weeks after inoculation. In the same acute cases, immunoconglutinain appeared at 6 weeks after inoculation and then slowly disappeared. The complement levels in the peracute and acute cases did not change appreciably.
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