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  • Title: [Psychic symptoms and personality of 50 patients with Cushing's syndrome (author's transl)].
    Author: Mazet P, Simon D, Luton JP, Bricaire H.
    Journal: Nouv Presse Med; ; 10(31):2565-70. PubMed ID: 7279633.
    Abstract:
    To determine whether patients with hypothalamo-pituitary Cushing's disease (HPC-D) can be distinguished on psychological grounds from these presenting with adrenal Cushing's syndrome (AC-S) or with ectopic ACTH syndrome, an in-depth psychological study including full personal, family and socio-professional history and a psychological interview was carried out in 50 patients with endogenous hypercortisolism. The results showed that psychiatric symptoms, such as anxiety and depression, are virtually constant in patients with either HPC-D or AC-S. They are, however, more pronounced in patients with HPC-D, and the latter condition is more likely to develop in subjects with either "psychosomatic" or pre-morbid depressive neurotic personality.
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