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  • Title: Quantitative EMG and histological carrier detection of Duchenne muscular dystrophy.
    Author: Scarlato G, Valli G, Meola G, Carenini L.
    Journal: J Neurol; 1977 Nov 01; 216(4):235-49. PubMed ID: 72807.
    Abstract:
    Seventy-nine women known as, or suspected to be, carriers of the Duchenne type of muscular dystrophy were examined. The 15 known carriers had an estimation of the CPK serum level and a manual quantitative EMG, which gave the high detection rate of 93%. The 64 suspected carriers had CPK determination and quantitative EMG, or CPK and muscle biopsy, and the value of each technic is discussed. The problem of giving a reassuring answer to women considered to be possible carriers on genetic criteria, but who are not really carriers, is solved if the results of all three tests are negative.
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