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  • Title: [Activity of cholesterol acyltransferase and cholesterol esterase in liver subcellular fractions of rabbits fed a cholesterol supplemented ration].
    Author: Finagin LK, Miroshnichenko ZN, Zatokovenko VF.
    Journal: Ukr Biokhim Zh (1978); 1981; 53(4):69-73. PubMed ID: 7281258.
    Abstract:
    The paper deals with the content of free and esterified cholesterol and also with the activity of cholesterol acetyltransferase and cholesterol esterase in the fraction of plasma membranes and liver subcellular fractions of rabbits fed a ration supplemented with cholesterol and sunflower oil. Under these conditions the content of cholesterol esters in the animals increases sharply in nuclei and cytosol and to a less extent--in microsomes and mitochondria. The activity of cholesterol acetyltransferase rises in the fractions of microsomes, nuclei and mitochondria being unchanged in the fractions of the plasma membranes. The activity of cholesterol esterase remains unchanged in all the fractions, being the highest in the fraction of the plasma membranes.
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