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  • Title: [Encouraging results with cytostatic therapy in metastasizing breast cancer (author's transl)].
    Author: Michlmayr G, Kratzer H, Denz H, Huber H.
    Journal: Wien Klin Wochenschr; 1981 Mar 20; 93(6):205-7. PubMed ID: 7281697.
    Abstract:
    58 women with metastatic breast cancer, non-responsive to hormone therapy, were treated with a modified CMF regimen. After progression the combination of adriamycin and vincristine was used. With CMF the response rate was 41% (10% complete remissions, 31% partial remissions), 38% showed no change, whilst progression of the disease was observed in only 21% of patients. The median duration of remission was about 8 months. Progression of the disease was treated by a combination of adriamycin and vincristine and remissions were obtained in 24% of cases. The median survival time of our patients from the time of tumour metastasis was 18.6 months and was dependent on the results of treatment.
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