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  • Title: [Flow properties of blood in women on oral contraceptives (author's transl)].
    Author: Heilmann L, Tauber PF, Siekmann U, Ludwig H.
    Journal: Zentralbl Gynakol; 1981; 103(12):678-86. PubMed ID: 7282169.
    Abstract:
    Erythrocyte deformability, whole-blood viscosity, haematocrit as well as fibrinogen and plasminogen concentrations were checked in 39 clinically intact women of whom 22 had been on oral contraceptives for upto five years. Also determined were several serum proteins, such as transferrin, coeruloplasmin, alpha-2 macroglobulin, alpha-1-trypsin, beta-lipoprotein, and inactivated complement component C3. -Seventeen women with intra-uterine devices were chosen to form a control group. Proteins with sensitivity to oestrogen as well as whole-blood viscosity were found to be increased whereas erythrocyte deformability was decreased. Yet, no haemodynamic manifestation took place ot those rheological parameters, since haematocrit declined or remained constant, and no change occurred to fibrinogen and plasminogen concentrations. Erythrocyte deformability, whole blood viscosity, hematocrit, as well as fibrinogen and plasminogen concentrations were checked in 39 clinically intact women of whom 22 had been on (OCs) oral contraceptives for up to 5 years. Also determined were several serum proteins, such as transferrin, coeruloplasmin, alpha-2 macroglobulin, alpha-1 trypsin, beta-lipoprotein, and inactivated complement C3. 17 women with IUDs were chosen to form a control group. Proteins with sensitivity to estrogen as well as whole blood viscosity were found to be increased, whereas erythrocyte deformability was decreased. Yet, no hemodynamic manifestation took place of those rheological parameters, since hematocrit declined or remained constant, and no change occurred to fibrinogen and plasminogen concentrations. (author's)
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