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  • Title: [Kallikrein-kinin system of the blood plasma in patients with infectious-allergic myocarditis].
    Author: Paleev NR, Ianovskaia MO, Gurevich MA, Surovikina MS.
    Journal: Kardiologiia; 1977 Sep; 17(9):84-8. PubMed ID: 72841.
    Abstract:
    The state of the blood plasma kallikrein-kinin system in infectious-allergic myocarditis was studied for the first time. Biological methods for the determination of kallikrein, kininogen, kininases, and free kinins were used. Changes in the activity of the kinin system were revealed in 92% of 38 individuals examined: activation in the first 2-4 months and exhaustion later (in 6-8 months). It was shown that the generally accepted clinico-laboratory criteria on myocarditis are not always informative. Determination of the components of the plasma kinin system is suggested as an additional diagnostic test. The use of kinin antagonists and inhibitors of the kinin system in the complex of drug therapy in infectious-allergic myocarditis is recommended.
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