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  • Title: Evidence for two distinct classes of unmyelinated nociceptive afferents in monkey.
    Author: Meyer RA, Campbell JN.
    Journal: Brain Res; 1981 Nov 09; 224(1):149-52. PubMed ID: 7284829.
    Abstract:
    Unmyelinated nociceptive afferents, responsive to intense mechanical and heat stimuli, exhibited either a quickly adapting or slowly adapting response to step increases in skin temperature. These two classes of C fibers were found to differ also in other properties. The quickly adapting C fibers had significantly lower thresholds to mechanical and heat stimuli, and smaller receptive field areas than the slowly adapting C fibers.
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