These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Collagen synthesis by human skin fibroblasts in culture: studies of fibroblasts explanted from papillary and reticular dermis.
    Author: Tajima S, Pinnell SR.
    Journal: J Invest Dermatol; 1981 Nov; 77(5):410-2. PubMed ID: 7288206.
    Abstract:
    Matched human skin fibroblast cultures were established from papillary and reticular dermis. Papillary dermal fibroblasts exhibited increased plating efficiency, exponential growth, and confluent density when compared with their matched reticular dermal cultures. Collagen synthesis by these cells, however, was essentially similar regardless of their origin. Relative collagen synthesis was similar at confluent densities. No differences in type specific collagen synthesis could be detected; relative amounts of types I and III collagens in culture media and types I, III, and AB collagens in the cellular pellet were similar. Type I pC collagen was consistently elevated in culture media from reticular dermal fibroblasts when compared to papillary dermal fibroblasts. The significance of this difference in procollagen processing is unknown.
    [Abstract] [Full Text] [Related] [New Search]