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  • Title: Cholinergic urticaria with associated angio-oedema.
    Author: Lawrence CM, Jorizzo JL, Kobza-Black A, Coutts A, Greaves MW.
    Journal: Br J Dermatol; 1981 Nov; 105(5):543-50. PubMed ID: 7295570.
    Abstract:
    Three patients are described who developed angio-oedema and urticaria after a hot bath challenge and physical exercise. In one patient this was accompanied by a fall in peak expiratory flow rate. Blood levels of smooth muscle biological activity, measured using a bio-assay, increased in all patients after experimental challenge. The association of angio-oedema with cholinergic urticaria is emphasized and possible mechanisms discussed.
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