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  • Title: [Regulation of the fluid state of the blood in thymectomized rats following intravenous thrombin administration].
    Author: Budazhapova DTs, Zagrebina LA, Kuznik BI, Tsybikov NN.
    Journal: Biull Eksp Biol Med; 1981 Sep; 92(9):285-7. PubMed ID: 7295983.
    Abstract:
    Experiments on rats have shown that after 3-4 months thymectomy leads to hypercoagulation followed by the increased level of fibrinogen. As compared with intact rats, the thymectomized animals manifested a less pronounced increase in the concentration of the anticoagulants, and less stimulation of fibrinolysis in response to intravenous injection of thrombin. This is regarded as one of the reasons for a more frequent death of the operated animals.
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