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  • Title: Polydipsia and abolition of angiotensin-induced drinking after transections of subfornical organ efferent projections in the rat.
    Author: Eng R, Miselis RR.
    Journal: Brain Res; 1981 Nov 23; 225(1):200-6. PubMed ID: 7296276.
    Abstract:
    Rats with transections of subfornical organ (SFO) efferent projections failed to drink to intravenous angiotensin-II (AII) but responded to intracellular dehydration and water deprivation and suppressed drinking when food deprived. However, the transected rats were polydipsic and polyuric. Thus SFO efferent projections mediate AII-induced drinking and may be involved in the regulation of body fluid balance.
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