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  • Title: Papillated squamous cell carcinoma in situ arising in a seborrheic keratosis.
    Author: Baer RL, Garcia RL, Partsalidou V, Ackerman AB.
    Journal: J Am Acad Dermatol; 1981 Nov; 5(5):561-5. PubMed ID: 7298922.
    Abstract:
    A 73-year-old man had developed a 27 x 60-mm seborrheic keratosis on his trunk. Some months previously, an 18 x 19-mm cauliflower-like area had developed within this seborrheic keratosis. Histologic examination showed a papillated squamous cell carcinoma in situ arising in a seborrheic keratosis. Seborrheic keratoses are the most common cutaneous neoplasms in man. Malignant changes are most unusual but should be suspected in lesions of unusual clinical appearance.
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