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  • Title: Levamisole in rheumatoid arthritis: a comparison with D-penicillamine.
    Author: Mowat AG, Mowat AM.
    Journal: J Rheumatol; 1981; 8(4):575-80. PubMed ID: 7299760.
    Abstract:
    Levamisole (150 mg 3 days/week) was compared with D-penicillamine (250 mg increments at 2--3 monthly intervals) in a single, blind independent observer trial of 1 years' duration in 32 patients with rheumatoid arthritis. The clinical responses, evident after 3 months, were comparable and significant. Six patients on levamisole and 4 on penicillamine withdrew due to side effects. In the subsequent open study 3 of 8 patients continued on levamisole for up to 4 years, while 6 of 9 remained on penicillamine. The findings are compared with those of other trials.
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