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  • Title: Effect of three bile acid binding polymers on the biosynthesis of 14C-cholesterol from 14C-sodium acetate in the rat.
    Author: Gilfillan JL, Huff JW.
    Journal: Res Commun Chem Pathol Pharmacol; 1981 Aug; 33(2):373-6. PubMed ID: 7302387.
    Abstract:
    The relative activity of three bile acid binding polymers in increasing cholesterol biosynthesis in the rat from 14C-acetate was determined by measuring blood levels of 14C-cholesterol after intraperitoneally administered 14C-acetate. CAT-FLOC and 3,3-ionene were 4-5 times more active than cholestyramine in this study which correlated well with the results of hypocholesteremic testing in dogs.
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