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  • Title: [Lipid analytic investigations concerning the establishment of the forms of primary hypercholesterolaemia in patients with myocardial infarction].
    Author: Wichmann T, Berndt K.
    Journal: Z Gesamte Inn Med; 1981 Jun 01; 36(11):370-6. PubMed ID: 7303762.
    Abstract:
    The influence of genetic factors in the development of the coronary heart disease can be particularly impressively clarified at the instance of the primary hyperlipoproteinaemias. The exact diagnostics of the genetically determined disturbances of lipometabolism in patients with infarction is, however, still connected with difficulties. Determinations of serum cholesterol and triglycerides, lipid-electrophoretic recognitions as well as determinations of LDL- and HDL-cholesterol in the serum cannot always outline with utmost clearness the proportion of primary hyperlipoproteinaemias in the morbidity of infarctions. Before this background the practical value of the radiochemical screening test worked up at the model of lymphocytes is emphasized, which allows a clear diagnosis of primary forms of hypercholesterolaemia according to pathogenetic viewpoints and thus renders possible also family examinations within the primary prevention of the coronary heart disease.
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