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  • Title: Malignant degeneration of benign cystic teratomas of the ovary.
    Author: Yakushiji M, Nishida T, Sugiyama T, Mitamura T, Natsuaki Y, Nagano H, Tsunawaki A, Kato T.
    Journal: Acta Obstet Gynaecol Jpn; 1981 Jul; 33(7):1095-8. PubMed ID: 7304134.
    Abstract:
    In 10 years from January 1971 to January 1981, 145 cases with cystic teratoma were treated at Kurume University Hospital, and malignant degeneration was seen in 7 of them (4.8%). Their age distribution was from 43 to 78 years, and the mean age was 59 years; the distribution shifted to the older side. The malignant degeneration was squamous cell carcinoma in all of the cases, and in 1 case carcinoma in situ leads to invasive carcinoma was observed continuously to a normal epithelium; it was interesting histogenetically. In their prognoses 3 out of 7 cases died (1 case dying from decrepitude) but the rest 4 have been surviving for 4 to 10 years.
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