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  • Title: Human sperm chromatin has a nucleosomal structure.
    Author: Wagner TE, Yun JS.
    Journal: Arch Androl; 1981 Nov; 7(3):251-7. PubMed ID: 7305541.
    Abstract:
    Digestion of human sperm chromatin with micrococcal nuclease reveals an 160 base pair (b.p.) DNA fragment that is further degraded to a series of DNA fragments remarkably similar to the micrococcal nuclease digestion products of eukaryote somatic cellular chromatin. DNase I digestion of human sperm chromatin also yields an identical pattern of DNA fragments to that observed upon DNase I digestion of somatic chromatin. These data, together with earlier electron microscopic observations, suggest a nucleosomal structure for human sperm chromatin.
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