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Title: Ribosomal core-particles as the target of ricin. Author: Zamboni M, Battelli G, Montanaro L, Sperti S. Journal: Biochem J; 1981 Mar 15; 194(3):1015-7. PubMed ID: 7306011. Abstract: Core-particles and split-proteins were prepared by treatment with ethanol and NH4Cl of control and ricin-treated Artemia salina ribosomes. No modifications of the ricin-treated split-proteins was detected by polyacrylamide-gel electrophoresis. Moreover, the split-proteins from ricin-treated ribosomes complemented control core-particles in poly(U)-directed phenylalanine polymerization. Conversely, ricin-treated core-particles remained totally inactive when supplemented with control split-proteins.[Abstract] [Full Text] [Related] [New Search]