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  • Title: Pattern formation along the anteroposterior axis of the chick wing: the increase in width following a polarizing region graft and the effect of X-irradiation.
    Author: Smith JC, Wolpert L.
    Journal: J Embryol Exp Morphol; 1981 Jun; 63():127-44. PubMed ID: 7310285.
    Abstract:
    A study is made of the widening of the chick limb bud that occurs after a graft of an additional polarizing region. Such buds are about 50% wider than controls, after 36 h. By contrast, growth along the proximodistal axis in unaffected. This widening is reduced by treating the host embryo with 10 Gy X-irradiation and the altered pattern of digits is consistent with a diffusible morphogen model for the specification of positional information along the anteroposterior axis.
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