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  • Title: [24 hour polygraphic study of the waking-up and falling asleep periods in patients with hepatic encephalopathy (author's transl)].
    Author: Baldy-Moulinier M, Besset A, Calvet B, Michel H.
    Journal: Rev Electroencephalogr Neurophysiol Clin; 1981 Sep; 11(1):123-32. PubMed ID: 7313246.
    Abstract:
    24 h sleep-waking EEG records of 23 patients with hepatic cirrhosis, 18 having hepatic encephalopathy, were studied. Comparison with a group of normal controls showed an increase in diurnal somnolence (08 h-22 h) and nocturnal waking (22 h-08 h) in all the patients. There was a significant reduction in the longest duration of waking and uninterrupted sleep periods in the patients with cirrhosis. Triphasic waves (characteristic of hepatic encephalopathy) were usually increased during waking and reduced in sleep. The factors involved in this disturbance of sleep-waking patterns in hepatic encephalopathy are discussed (cerebral monoamines, false neurotransmitters, cerebral arteriovenous shunts...).
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