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  • Title: Criteria of maturity and age of red blood cells.
    Author: Gross J, Rapoport SM, Rosenthal S, Syllm-Rapoport I.
    Journal: Acta Biol Med Ger; 1981; 40(4-5):665-8. PubMed ID: 7315113.
    Abstract:
    Any work on red blood cells requires information about the characteristics of a cell population. Using buoyant density separation of red blood cells (RBC) in a dextran medium during a bleeding anemia of rabbits cell-physiological, ribosomal, mitochondrial and cytoplasmic criteria were estimated in order to select parameters useful for the characterization of a given RBC population according to its developmental stages. Useful criteria for an unknown overall RBC population are reticulocyte count and aspartate amino transferase, or glucose-6-phosphate dehydrogenase activity or creatine concentration. Useful additional criteria for reticulocytes are the mean cellular volume and the RNA concentration.
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