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  • Title: [Variations in parathormone serum levels during treatment of Paget's disease with calcitonin of human or salmon origin (author's transl)].
    Author: Heynen G, Franchimont P, Gaspar S, Gysen P, Kanis JA.
    Journal: Ann Endocrinol (Paris); 1981; 42(3):265-75. PubMed ID: 7316460.
    Abstract:
    Biological effects of increasing doses of human and salmon calcitonin (CT) have been studied in 17 patients suffering from Paget's disease of bone. Results show a dose response relationship on indirect indices of bone turn-over. The plateau phenomenon occurs with both CT and more rapidly with the lower dosage. There is also a transient increase in parathyroid activity during the period of time when bone turn-over is decreasing. Calciuretic effect was more pronounced with salmon than with human CT.
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