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  • Title: Daily profile of baroreflex sensitivity and the variability of blood pressure in essential hypertensive patients.
    Author: Ogawa J, Arai S, Takata S, Ikeda T, Takabatake T, Hattori N, Nomura G.
    Journal: Clin Sci (Lond); 1981 Dec; 61 Suppl 7():157s-159s. PubMed ID: 7318316.
    Abstract:
    1. We have monitored intra-arterial pressure continuously throughout the day and analysed every beat by computer. 2. Baroreflex sensitivity (ms/mmHg) was measured four times a day (07.00, 12.00, 17.00 and 20.00 hours) in seven patients and three times a day (07.00, 12.00 and 17.00 hours) in 23 patients. The diurnal variation of baroreflex sensitivity in individual patients was 0--5.3 ms/mmHg and was not consistent. Mean baroreflex sensitivity was reduced in hypertensive patients compared with normotensive subjects. 3. A negative correlation was seen between baroreflex sensitivity and the variability of systemic blood pressure. 4. Baroreflex sensitivity was well correlated with the variability of heart rate.
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