These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Search MEDLINE/PubMed
Title: Evaluation of amphetamine-induced in vivo electrochemical response. Author: Dayton MA, Ewing AG, Wightman RM. Journal: Eur J Pharmacol; 1981 Oct 22; 75(2-3):141-4. PubMed ID: 7318902. Abstract: A carbon fiber microelectrode is shown to give a potential-dependent dopamine-selective response in rat brain tissue. However, distinct evidence for dopamine release is not obtained with intraperitoneal amphetamine administration (1.8 or 3.7 mg . kg-1). In rats which have been unilaterally depleted of dopamine, the change in electrochemical signal obtained in the lesioned striatum is very similar to that measured on the non-lesioned side following amphetamine administration. This indicates that substances other than dopamine contribute to the observed signals.[Abstract] [Full Text] [Related] [New Search]