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  • Title: New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. II. Structure of 2-hydroxyaklavinone and new aklavinone glycosides.
    Author: Matsuzawa Y, Yoshimoto A, Shibamoto N, Tobe H, Oki T, Naganawa H, Takeuchi T, Umezawa H.
    Journal: J Antibiot (Tokyo); 1981 Aug; 34(8):959-64. PubMed ID: 7319928.
    Abstract:
    Four blocked mutants of aclacinomycin-producing Streptomyces galilaeus MA144-M1 produced new anthracyclinones; 2-hydroxyaklavinone, its non-esterified analog and 2-hydroxy-7-deoxyaklavinone, several new anthracyclines; 2-deoxyfucosyl-2-deoxyfucosyl-rhodosaminylaklavinone (MA144 U1), 2-deoxyfucosyl-rhodosaminylaklavinone (MA144 U2) and five aklavinone glycosides devoid of amino sugar, designated as MA144 U5, U6, U7, U8 and U9.
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