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  • Title: [Experience with polychemotherapy based on cell synchronization, via intra-arterial infusions. Preoperative treatment of maxillofacial tumors].
    Author: Szabó G, Takács L, Kovács A, Skalitzki J.
    Journal: Rev Stomatol Chir Maxillofac; 1977; 78(5):357-62. PubMed ID: 73213.
    Abstract:
    Chemotherapy based upon cellular synchronisation via intra-arterial infusion was used in the treatment of 21 carcinomas of the maxillo-facial region. These tumours had never been treated either by surgery, nor by irradiation. This pre-operative treatment was not aimed at altering ghe indication for the type of operation decided upon at the outset. It was found that a combination of Vincristine, Bleomycine, Methotrexate and Dibromdulcide was more satisfactory than other types of chemotherapy. The most important complication of the method was a thrombosis of the common carotid.
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