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  • Title: Pilomatrixoma (benign calcifying epithelioma of Malherbe).
    Author: O'Grady RB, Spoerl G.
    Journal: Ophthalmology; 1981 Dec; 88(12):1196-7. PubMed ID: 7322467.
    Abstract:
    A 24-year-old white man had a large subcutaneous discolored tumefaction of the right lower lid, successfully treated by two separate incision and drainage procedures. Microscopic appearance initially suggested basal cell epithelioma, but further studies provided a correct diagnosis of pilomatrixoma (calcifying epithelioma of Malherbe). This lesion probably represents aberrant primitive germ cells differentiating towards a hair matrix cell. Basaloid and squamoid (shadow) cells with or without focal calcifications in shadow cell areas are typical, and the clinical presentation is also highly suggestive of pilomatrixoma.
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