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  • Title: Derivatives of n-aryl-N-amino piperazines as potential cardiovascular agents.
    Author: Dubey M, Verma VK, Sharma M, Shanker K, Sinha JN, Bhargava KP, Kishor K.
    Journal: Pol J Pharmacol Pharm; 1981 Oct; 33(3):349-57. PubMed ID: 7322947.
    Abstract:
    24 new substituted piperazino guanidines and 34 substituted benzylideno- or benzylamino-4-phenyl piperazines were synthesized and evaluated for their cardiovascular activity. Several compounds of the above two series exhibited vasopressor or vasodepressor activity without modifying the carotid occlusion (CO) and noradrenaline (NA) induced pressor responses.
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