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  • Title: Nasal allergy in spinning mill workers and the possibility of allergenicity of chemical fibers and cotton linters.
    Author: Uchikoshi S, Nomura K, Saitoh S, Komatsu N, Chien C, Miyake H.
    Journal: Tokai J Exp Clin Med; 1981 Oct; 6(4):363-71. PubMed ID: 7324077.
    Abstract:
    During a three-year period from 1976, we examined fifty eight patients with nasal allergy who worked in spinning mills or handled sewing machines. Skin tests and procative nasal tests were performed on these patients with crude and fractionated extracts from cotton linters, cotton cloth and chemical fibers. The crude aqueous antigens were extracted in dextro-phenol solution and fractionated by Saphadex G-100. It was possible that the cotton and chemical fibers included components which were the cause of hypersensitivity, but there is still doubts concerning their reaction as irritant substances. Serum specific IgE antibody was found in extracts from chemical fiber. Therefore, spinning mill dust acts as an irritant of the nose add the possibility of antigenicity of the dust for immediate type nasal allergies can not be denied from the present study.
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